Calculate the Gibbs free energy for the binding of one sequence with 260.000 different sequences.

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U1_1337
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Joined: 11/28/2017

Hi,

I'm new to the mfold forum, so please excuse if this is an obvious question.

For my project I would like to calculate the Gibbs free energy for the binding of one sequence with every possible sequence of a certain length (=260.000 sequences ). All sequences will be 11 nt long and I was wondering, if there would may be a way to automatically generate those calculated Gibbs free energy for every sequence.

Or is the way to calculate those values open source and I just didn't find it?

Thank you in advance and greetings from germany,
Johannes