tutorial for mFold and UNAFold
Could anyone prepare a tutorial for mFold and UNAFold?
I'm not familiar with perl scripts and linux, and after several days looking many documents around the many websites and this site (man pages and froum) I mixed up and could not run mFold or UNAFold for predicting RNA secondary structures :(
Could anyone help me (and many others like me) by preparing step by step tutorial running these soft-wares on windows and linux.
Thank you in advance
The UNAFold web server is currenly an amalgamation of two existing web servers: mfold & DINAMelt. The aim of this web site is to integrate the existing servers and to expand by developing algorithms and software that will provide new services to the scientific community.
MFold is an adaptation of the mfold package (version 2.3) by Zuker and Jaeger that has been modified to work with the Accelrys GCG (GCG). Their method uses the energy rules developed by Turner and colleagues to determine optimal and suboptimal secondary structures for an RNA molecule and the energy rules compiled and developed by SantaLucia and colleagues to determine optimal and suboptimal secondary structures for a single-stranded DNA molecule.